Projects · de-risking cases
Projects: engineering and scientific de-risking cases
Real projects, anonymized under NDA. Each one is task → method → result with numbers from the reports. The work was done for clients; we don't disclose the client, product or country — details come on a diagnostic call.
Medicinal chemistry · rechecking the shortlist
Selectivity read: 1401 “antagonists” → 19 confirmed
A manual check of the direction of action filtered false hits and brought two calculation methods into agreement (r = +0.44).
Client and details are under NDA, shared on a diagnostic call.
OpenPlant engineering · utilities
Independent HVAC & chilled-water check for a GMP plant
The recheck exposed a 137 kW double-count and 22 deviations from spec (6 critical) — before the contract was signed.
Client and details are under NDA, shared on a diagnostic call.
OpenGeneric launch · entry economics
Generic to market: the sales plan vs the ceiling of demand
The planned 50,000 packs equalled the ceiling of all demand; as a standalone business, entry loses money.
Client and details are under NDA, shared on a diagnostic call.
OpenFormulation · clinical rationale
A “satiety-enhancer” supplement: sound formula, unprovable claim
Preformulation plus an evidence-base audit: the headline claim can't be proven, but a neighbouring claim has strong support.
Client and details are under NDA, shared on a diagnostic call.
OpenImport substitution · synthesis
Candidate molecules with simple synthesis for localization
Screening by synthesizability, a “synthesis difficulty / market attractiveness” quadrant, and an independent red-team validation.
Client and details are under NDA, shared on a diagnostic call.
OpenBuccal delivery
Oral films: how much active really fits
Dose-capacity calculation and load limits for the active — verifiable limits instead of promises.
Client and details are under NDA, shared on a diagnostic call.
OpenNutraceuticals · business case
Supplement portfolio: what to make and in which channel
SKU scoring, channel margins, scenarios and a financial model — a director's verdict, not generic advice.
Client and details are under NDA, shared on a diagnostic call.
OpenMarket assessment · new market
Niches and the economics of entering a new national market
Niche assessment with plant-CAPEX and retail-price anchors, an SKU business case and revenue scenarios.
Client and details are under NDA, shared on a diagnostic call.
OpenRegulatory · patent strategy
Generic entry before the patent cliff — registration mechanisms
Compulsory registration and licensing: how to enter while the patent is still in force, and where the legal limits are.
Client and details are under NDA, shared on a diagnostic call.
OpenFormulation · non-oral form
Two non-oral forms of one active substance
Carrier physicochemistry, pharmacokinetics, patent clearance and applicability limits — with stability caveats.
Client and details are under NDA, shared on a diagnostic call.
OpenPositioning · herbal product
Taking a herbal product to a foreign market
A comparison against an analogue, a manufacturer map, and positioning for a specific market given the category's regulatory status.
Client and details are under NDA, shared on a diagnostic call.
OpenEvery case has the same shape
Task → method → result, with numbers from the reports and honest caveats — what's measured, what's an estimate, what's from the client. A negative result is still a result: it saves the client money before it's spent.
Need this on your project?
Message us — we'll show the method and scope the de-risking to your task.